EVectiveness bulletins Antimicrobial prophylaxis in colorectal surgery
نویسندگان
چکیده
This paper is based on EVective Health Care, volume 4, no 5, which is an update of a systematic review of randomised controlled trials (RCTs) examining the eVectiveness of diVerent antimicrobial regimens used for the prevention of surgical wound infection in patients undergoing colorectal surgery. Details of the review’s methodology are published elsewhere. 2 Hospital acquired infections, of which surgical wound infections are among the most common, cost the NHS over £170m in England alone. These infections increase morbidity and mortality, prolong hospital stay, and increase the cost of medical care. 5 Colorectal surgery is associated with a particularly high risk of surgical wound infection due to a high risk of contamination by bacteria from the contents of the large bowel. The use of antimicrobial prophylaxis can help to reduce the risk of wound infections after colorectal surgery from about 40% to around 11%. 2 Over the past 20 years, the practice of using antimicrobial prophylaxis before surgery has evolved greatly, with such antimicrobial agents accounting for about half of all antibiotics prescribed in hospitals. Uncertainty exists, however, about which drugs should be used, and about the timing, duration, and route of administration. In addition, thought needs to be given to ways of reducing the spread of antimicrobial resistance.
منابع مشابه
Antimicrobial prophylaxis in colorectal surgery
Antimicrobial prophylaxis in colorectal surgery The contents of this bulletin are likely to be valid for around one year, by which time significant new research evidence may have become available. s Antimicrobial prophylaxis is effective for the prevention of surgical wound infections in colorectal surgery and should be used. s No 'gold standard' regimen can be identified. There is no differenc...
متن کاملAntimicrobial prophylaxis in colorectal surgery
Antimicrobial prophylaxis in colorectal surgery The contents of this bulletin are likely to be valid for around one year, by which time significant new research evidence may have become available. s Antimicrobial prophylaxis is effective for the prevention of surgical wound infections in colorectal surgery and should be used. s No 'gold standard' regimen can be identified. There is no differenc...
متن کاملAntimicrobial prophylaxis in colorectal surgery: focus on ertapenem
Despite improvement in infection control measures and surgical practice, surgical site infections (SSIs) remain a major cause of morbidity and mortality. In colorectal surgery, perioperative administration of a suitable antimicrobial regimen that covers both anaerobic and aerobic bacteria is universally accepted. In a prospective, double-blind, randomized study ertapenem was recently found to b...
متن کاملAntimicrobial prophylaxis in colorectal surgery: a systematic review of randomised controlled trials.
متن کامل
Evaluation of a preventive surgical site infection bundle in colorectal surgery.
OBJECTIVE To assess the effectiveness of a protocol for prevention of surgical site infection (SSI) in colorectal surgery. PATIENTS AND METHODS Evaluation of 2 cohorts of patients undergoing colon and rectal surgery in a tertiary public hospital: A historical cohort (2008-2011) and a prospective one (after the implementation of the program in 2012). The main measures established were: Adequac...
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تاریخ انتشار 1999